• ArtsandLectures twitter avatar
    #SBSummerCinema fun continues w/The Big Sleep, perhaps the definitive #BOGIEandBACALL film https://t.co/AxlPbHUeIh https://t.co/mMJGysYNIn
    2 hours 45 min ago
  • ucsantabarbara twitter avatar
    Why does Greek artist Evdokimos Tsolakidis feel bad for Helen of Troy? Find out at his production of “Helen." https://t.co/0XFlqQuEy0
    3 hours 3 min ago
  • UCSBLibrary twitter avatar
    "A Snapshot of a 21st Century Librarian, story in The Atlantic: https://t.co/FuBNWdoyhY https://t.co/yZCrDa4Qr3
    6 hours 27 min ago
  • ArtsandLectures twitter avatar
    Dynamic events. Fascinating people. Captivating stories. https://t.co/PFT86142o9 #NatGeoLive! https://t.co/U1yu2hmsgE
    7 hours 30 min ago
  • ArtsandLectures twitter avatar
    RT @KCRWinSB: Sex, murder, & mystery join us @ the SB County Courthouse Friday night for The Big Sleep https://t.co/vSIq7xC2FR https://t.co…
    16 hours 2 min ago
  • ucsantabarbara twitter avatar
    Join #UCSB & #TheCousteauFellowship2016 in empowering young filmmakers and activists! https://t.co/PQdTv5hK87 https://t.co/SW0cLTP1kb
    20 hours 39 min ago
  • UCSBengineering twitter avatar
    2015 MAT Alumnus co-created wearable tech alcohol sensors #UCSBengineering #UCSBCOE50 https://t.co/o9vt0bcG1M https://t.co/pQJGypdVpo
    21 hours 50 min ago
  • UCSB_GradPost twitter avatar
    Finding Funding Workshop on August 3 https://t.co/1Cvh6qsDAg #UCSB #ucsbgradpost
    1 day 13 min ago
  • UCSBengineering twitter avatar
    UCSB Engineers do amazing work. Alum @ntopliffe has designed infrastructure for hospitals around the world. https://t.co/86mcdn1TRK
    1 day 4 hours ago
  • UCSBengineering twitter avatar
    @ntopliffe Very cool work on the new Stanford Hospital, congratulations.
    1 day 4 hours ago
  • UCSBgauchos twitter avatar
    Women's Volleyball Earns AVCA Academic Team Award for Second Straight Year https://t.co/GPlSC2O8wy
    1 day 4 hours ago
  • UCSBgauchos twitter avatar
    Women's Volleyball Earns AVCA Academic Team Award for Second Straight Year https://t.co/GPlSC35JV8
    1 day 4 hours ago

UCSB Nanotechnology Breast Cancer Study Receives $2.8 Million Grant

Wednesday, October 7, 2009 - 17:00
Santa Barbara, CA

Erkki Ruoslahti, professor at UC Santa Barbara's Burnham Institute for Medical Research, is the recipient of a $2.8 million award from the Department of Defense for research into detection and therapies for breast cancer using nanotechnology.

"The prevalence of breast cancer and the large number of deaths from this disease underscore the need for a paradigm shift in the strategies toward developing a cure for breast cancer," said Ruoslahti. "The traditional first line approach still relies on surgery with chemotherapy for late stage or palliative effect. However, this regimen often fails to eradicate the disease, leading to recurrence and drug-induced side effects that adversely affect quality of life. We envision that the cure for breast cancer can be achieved by strategically integrating early detection with synergistic therapies. We believe that nanotechnology-based engineering solutions can provide the needed changes to drastically improve the cure rates."

Ruoslahti's team is developing new diagnostic tools that will improve early detection while reducing unnecessary procedures. The use of targeted nanoparticles as a contrast agent can improve sensitivity and provide molecular information on suspect lesions that cannot be obtained with MRIs alone. The novel in-vivo tests will add to the diagnostic arsenal by providing information not only on the presence of a tumor, but also on the stage of tumor development.

"As nanoparticles can be engineered to perform many functions, something that cannot be achieved with a simple drug, we can add a specific targeting function to the particles," said Ruoslahti. "Targeting can concentrate the therapeutic agent in the tumor, improving the efficacy of the treatment and reducing damage to healthy tissues. The diagnostic and therapy functions will be synergistic in that the diagnostic methods will provide information on the efficacy of individual homing peptides in targeting the tumor."

"Hybrid Nanotechnologies for Detection and Synergistic Therapies for Breast Cancer" is the name of the award that will run through October 20, 2014.

The awarding agency is the Department of Defense, under the Congressionally Directed Medical Research Programs (CDMRP). It is part of the Breast Cancer Research Program, U.S. Army Medical Research and Materiel Command. Collaborators on this grant are Roger Tsien of UC San Diego and Shiladitya Sengupta of Brigham and Women's Hospital, Boston. They will each receive their own awards.

Issued: 10/7/09;

Corrected: 10/8/09

Erkki Ruoslahti