• UCSBgauchos twitter avatar
    Softball: UCSB Defeats Nebraska-Omaha, Wins Second Straight in Extra Innings https://t.co/K6gXfECU2d
    2 hours 14 min ago
  • brenucsb twitter avatar
    New study reveals dissolved oxygen levels are dropping in oceans around the world as a result of #climatechange: https://t.co/yC08zCybSo
    6 hours 31 min ago
  • ucsantabarbara twitter avatar
    UCSB’s Nikkei Student Union will present “Manzanar Fishing Club” as part of a Day of Remembrance on Feb. 21. https://t.co/rX387XzrIs
    6 hours 47 min ago
  • UCSBgauchos twitter avatar
    Gauchos have a successful day with a win against UC Davis 4-0 and St. Mary's 4-3 https://t.co/eBmdVbdmkW
    15 hours 51 min ago
  • UCSBgauchos twitter avatar
    .@UCSB_Baseball can't solve Arriaga, fall 1-0 at LMU. Series rubber match tomorrow at 1 PM! RECAP >>>… https://t.co/F8nk3CCoag
    17 hours 28 min ago
  • UCSBgauchos twitter avatar
    Softball: Gauchos Defeat Pacific in Extra Innings, Fall to Stanford https://t.co/R8MtFxyclg
    18 hours 1 min ago
  • UCSBgauchos twitter avatar
    Women's Tennis: UC Santa Barb. 4, UC Davis 0 (Final) Gauchos win third straight, defeat UC Davis 4-0 https://t.co/vDAcGmp1yY
    18 hours 52 min ago
  • UCSBgauchos twitter avatar
    WBB: Gauchos Gobbled Up By Long Beach State Pressure, Fall 59-45 In Third of Four Game Road Trip https://t.co/rOVVIVM7ag
    19 hours 12 min ago
  • UCSBgauchos twitter avatar
    Gauchos Drop 66-48 Decision to Long Beach State https://t.co/WEEbdyqn0E
    20 hours 34 min ago

BACTERIAL 'KILLING MACHINES' SUBJECT OF PLOUS LECTURE

Thursday, April 30, 1998 - 17:00
Santa Barbara, CA

When it comes to bacterial disease, the wake-up call has been sounded, warns microbiologist Michael J. Mahan, this year's Plous Award honoree.

"Our microbial defenses are crumbling as superior pathogens have emerged that can no longer be controlled by available antibiotics," says Mahan, assistant professor of molecular, cellular, and developmental biology at the University of California, Santa Barbara.

"Many of these bacteria that were once merely a nuisance have recently evolved into efficient killing machines," says Mahan. "Over 30 new diseases have emerged within the last 20 years."

Mahan will delivered the 40th annual Harold J. Plous Memorial Lecture, titled "Emerging Pathogens: What You Don't Know Can Kill You," at Girvetz Theater on Thursday, April 30. The talk will focussed on the danger in the food supply, common sense tips to reduce the risk of infection, and research aimed at increasing the safety of food.

Mahan studies salmonella, a pathogen that infects 4 million people in the United States every year. There are 2,500 different strains of salmonella, which are responsible for causing diseases ranging from food poisoning to typhoid fever, says Mahan. "Very similar strains of salmonella can give enormously different disease manifestations," he said, noting that young children are the most vulnerable.

Mahan's research is focused on understanding the mechanisms by which bacterial pathogens cause disease. He has developed a new approach to the isolation of bacterial virulence factors, termed IVET for in vivo expression technology. IVET allows researchers to observe how bacteria trigger their killing functions in living cells. A report on this research is

published in this month's "Proceedings of the National Academy of Sciences."

Mahan joined the UCSB faculty in 1993 after several years as a post-doctoral fellow at Harvard Medical School. In 1994 he received the Newcomb-Cleveland Prize from the American Association for the Advancement of Science for the outstanding paper published in Science. He is also recipient of an American Cancer Society Junior Faculty Science Research Award and a Beckman Young Investigator Award.

The Plous Award honors the assistant professor in the College of Letters and Science who has made the greatest contribution to the intellectual life of the university through outstanding teaching, research, and community service. Harold J. Plous, for whom the award is named, was an assistant professor of economics at UCSB who died in 1957.