• UCSBgauchos twitter avatar
    No. 17 Oregon State Cruises Past UCSB https://t.co/CzMUcPZx5O
    21 hours 3 min ago
  • ucsantabarbara twitter avatar
    Thank you to our firefighters, first responders, and all individuals who are working tirelessly to protect our Sant… https://t.co/Op4wafDFvf
    1 day 1 hour ago
  • ucsantabarbara twitter avatar
    The #RedCross emergency shelter at #UCSB is open and taking in #ThomasFire evacuees. https://t.co/91KqTnQZL6 https://t.co/91KqTnQZL6
    1 day 2 hours ago
  • ArtsandLectures twitter avatar
    A&L regretfully announces the cancellation of tonight’s Blind Boys of Alabama Holiday Show due to the latest condit… https://t.co/kWZGJYgC5p
    1 day 4 hours ago
  • ucsantabarbara twitter avatar
    A reminder about the #RedCross emergency shelter on the #UCSB campus for #ThomasFire evacuees. https://t.co/91KqTnQZL6
    1 day 6 hours ago
  • ArtsandLectures twitter avatar
    Six-time Grammy Award winners The Blind Boys of Alabama will bring some much-needed tidings of joy to our fire-scar… https://t.co/WYXObMouQP
    1 day 23 hours ago
  • UCSBgauchos twitter avatar
    UCSB-LMU Women's Basketball Game Moved to LMU on Monday https://t.co/F4N1uaSWv3
    2 days 4 hours ago
  • AS_UCSB twitter avatar
    RT @tblucsb: Missed the 10:30 a.m. deadline? @AS_UCSB director Marisela Marquez will continue to work with students who need financial aid…
    2 days 5 hours ago
  • UCSBgauchos twitter avatar
    Cotterill, Hauschild Earn All-American Honors https://t.co/VIIel1x2ZS
    2 days 6 hours ago

BACTERIAL 'KILLING MACHINES' SUBJECT OF PLOUS LECTURE

Thursday, April 30, 1998 - 17:00
Santa Barbara, CA

When it comes to bacterial disease, the wake-up call has been sounded, warns microbiologist Michael J. Mahan, this year's Plous Award honoree.

"Our microbial defenses are crumbling as superior pathogens have emerged that can no longer be controlled by available antibiotics," says Mahan, assistant professor of molecular, cellular, and developmental biology at the University of California, Santa Barbara.

"Many of these bacteria that were once merely a nuisance have recently evolved into efficient killing machines," says Mahan. "Over 30 new diseases have emerged within the last 20 years."

Mahan will delivered the 40th annual Harold J. Plous Memorial Lecture, titled "Emerging Pathogens: What You Don't Know Can Kill You," at Girvetz Theater on Thursday, April 30. The talk will focussed on the danger in the food supply, common sense tips to reduce the risk of infection, and research aimed at increasing the safety of food.

Mahan studies salmonella, a pathogen that infects 4 million people in the United States every year. There are 2,500 different strains of salmonella, which are responsible for causing diseases ranging from food poisoning to typhoid fever, says Mahan. "Very similar strains of salmonella can give enormously different disease manifestations," he said, noting that young children are the most vulnerable.

Mahan's research is focused on understanding the mechanisms by which bacterial pathogens cause disease. He has developed a new approach to the isolation of bacterial virulence factors, termed IVET for in vivo expression technology. IVET allows researchers to observe how bacteria trigger their killing functions in living cells. A report on this research is

published in this month's "Proceedings of the National Academy of Sciences."

Mahan joined the UCSB faculty in 1993 after several years as a post-doctoral fellow at Harvard Medical School. In 1994 he received the Newcomb-Cleveland Prize from the American Association for the Advancement of Science for the outstanding paper published in Science. He is also recipient of an American Cancer Society Junior Faculty Science Research Award and a Beckman Young Investigator Award.

The Plous Award honors the assistant professor in the College of Letters and Science who has made the greatest contribution to the intellectual life of the university through outstanding teaching, research, and community service. Harold J. Plous, for whom the award is named, was an assistant professor of economics at UCSB who died in 1957.